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Joined 3 years ago
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Cake day: July 4th, 2023

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  • “Expensive and exclusive” is part of the brand.

    That’s why the MacBook Neo is putting up numbers, because it’s expensive and exclusive. /s

    IME Apple phones often end up cheaper over the life of the device because they get updates for 5+ years. Not everyone needs a Pro with maxed out specs. They’re hardly exclusive, either; have you seen how common they are? Every other person in the states has an iPhone. They’re often giving them away with cell phone plans. Getting a previous gen iPhone is probably one of the best values because it’s still fast and will be supported for years to come, but it’s significantly discounted.





  • Everything is virus: one of the theories of how cells went from RNA to DNA is viruses.

    Forterre (2006) proposed that early cellular lineages diversified while still harboring RNA genomes, with viruses and cells coexisting from the beginning. In his model, the first fixation of DNA occurred in viruses, which subsequently transferred the enzymes necessary for DNA synthesis and maintenance into independent cellular lineages. Thus, RNA genomes in ancestral cells were converted into DNA genomes via viral intermediates (Forterre, 2002, 2006). The structural and functional differences among cellular replication systems would then reflect the independent viral origins of DNA replication machinery.

    https://www.sciencedirect.com/science/article/abs/pii/S0303264725002813









  • What is the ideal amount of biomass for humans? Same question for agricultural land. What’s the ideal amount? I’m torn between thinking this is just how things go or maybe I’m just terribly ignorant. At some point the majority of biomass was dinosaurs or something, so what? That’s the ebb and flow of life. It wasn’t the biomass of dinosaurs that caused their extinction. How do these biomass stats indicate overpopulation?

    I can’t disagree with the industrial farming and overall ecosystem points you raise but the biomass bits seem awfully arbitrary.

    I’d also say feeding 50% of the world’s population for 2% of the world’s energy seems pretty damn efficient.







  • Can you explain further? I’m a biochemist / medical lab scientist, and between my studies in genetics, human sexuality, and endocrinology, it seems pretty well figured out. Between “normal” X/Y chromosomes, various chromosomal abnormalities (X, XXX, XXY, XYY, etc), and mutations like androgen insensitivity syndrome it seems there is significant causal data. Not sure if they’ve studied these with knockout mice but it’s well beyond inference at this point.

    I’m not sealioning here, it has been like a decade since I was actively learning this stuff and I’m sure there have been more discoveries. In general though it seems like we know the genetics, we know the hormones and receptors involved, the developmental process and various maladies are known, etc.